At least seven people were killed and three others severely injured Sunday when a train coming from Upper Egypt ran over a car that was crossing the railway in Giza's Al-Ayyat during foggy weather, Ahram Arabic news website reported.
The injured are in critical condition and have been transferred to the hospital.
Al-Ayyat witnessed two train crashes in 2009 that killed at least 50 people.
On 20 February 2002, a train caught fire in Al-Ayyat, killing at least 380 people, the worst railway disaster in Egypt's history.
Egypt's railway system is operated manually, with employees responsible for managing the opening of the crossings by communicating with the drivers--a practice that is considered unsafe and unreliable.