Four people, including a child, were killed on Sunday when a microbus collided with a car on a highway in Egypt's southwest, Al-Ahram Arabic news website reported.
Another five people were injured and referred to a nearby hospital.
The highway links the southern city of Assiut to the western oasis of Kharga.
Road accidents are commonplace in Egypt due to ill-maintained roads as well as a disregard for traffic laws.
Over 6,000 were killed and 24,000 injured in road accidents in 2014, Egypt's Central Agency for Public Mobilisation and Statistics (CAPMAS) recorded in their latest report.