Egyptian police thwarted a plan to carry out a suicide attack against security personnel in the North Sinai city of Al-Arish, the interior ministry said in an official statement on Tuesday.
The officers killed the would-be bomber at 1am on Tuesday morning, during a nightly curfew in the city, after he refused to stop at a police roadblock.
After inspection, a large amount of explosives were found in the truck.
The assailant was also wearing an explosive belt.
In August, a roadside bomb killed two Egyptian policemen as they were travelling in an armoured vehicle in Al-Arish, according to the interior ministry.
Attacks in the North Sinai cities of Rafah, Al-Arish and Sheikh Zuwaid, primarily targeting security forces, have become frequent in the two years since the ouster of Islamist president Mohamed Morsi.