Six army personnel were killed during a militant attack on a security checkpoint in the North Sinai city of Arish, the army's spokesman said in a statement on Friday.
Army forces are currently combing the area to arrest the militants, who attacked the army personnel with grenades and automatic fire and then fled.
A number of militants were killed and injured when the army personnel returned fire, the statement added.
Egyptian security forces are battling a North Sinai-based Islamist insurgency that intensified following the ouster of Islamist president Mohamed Morsi in 2013.
Hundreds of security personnel have been killed by militants in recent years, while the army says it has killed hundreds of militants in security campaigns in the governorate.