Khaled Dawoud, the head of Egypt's Dostour (Constitution) Party, announced his resignation from the post on Sunday.
In a statement, veteran journalist Dawoud explained that his decision comes as an attempt to end the internal disagreements in the party, calling for new internal elections for the first time since four years.
Dawoud also announced that Sayed Kassem, the party's co-founder and honorary leader, would act as interim party leader until new elections could be held.
"I appreciate the efforts of Ambassador Sayed Kassem as well those of members of the party's general secretariat with whom I worked over the past year and half under very hard political circumstances that do not allow opposition parties to exist in the first place," Dawoud said in his statement before wishing luck to all party members.
Founded by Nobel laureate Mohamed ElBaradei in 2012, Dostour Party leadership has had several disagreements over the timing of internal elections and candidate eligibility.