Police fired teargas on Friday afternoon at a march by supporters of ousted president Mohamed Morsi in the Talbia area in Haram disrict.
According to Ahram Arabic news website, security forces also fired teargas at hundreds of Morsi loyalists in Cairo's upscale district of Maadi, Nasr City and Giza's Mohandseen.
Meanwhile, according to MENA, Security forced fired teargas to disperse Islamist demonstrators in the city of Suez as they clashed with police down Al-Yahodiya street near Al-Hoda Mosque.
A police officer was injured by a rock thrown by Islamists who were protesting in Fayoum, Upper Egypt, without a permit.
Several marches by supporters of ousted president Mohamed Morsi have taken place in locations around Cairo, Giza and other provincial cities following Friday prayers.
Hundreds of protesters left mosques after Friday prayers in the Cairo districts of Helwan, Maadi, Nasr City, and over the river in parts of Giza, holding pictures of Morsi and posters showing the four-fingered Rabaa sign, a symbol of his followers.
Demonstrators also chanted against the military and police.
The protests was called for the pro-Morsi National Alliance to Support Legitimacy, in support of 21 female protesters in Alexandria who were given harsh prison sentences last week.
In Giza's Haram, locals holding pictures of Minister of Defence Abdel-Fatah El-Sisi attempted earlier to disperse a march by the Muslim Brotherhood before police fired teargas at protesters.
Police say they arrested eight protesters in Giza.
The ministry of health has not yet released figures on injuries for the day.
An Egyptian court sentenced 14 female protesters to 11 years in jail and placed seven underage girls in juvenile detention for taking part in clashes during a pro-Morsi protest in the Mediterranean city of Alexandria. The women and girls have maintained that they were protesting peacefully.
Egyptian security forces had stepped up their presence around Cairo and Giza on Friday, in anticipation of the demos.
Under new legislation on protests, issued last week by interim President Adly Mansour, demonstrators must submit plans for their protests to the authorities at least three days prior. Failure to do so can result in fines or jail terms.