Military police on Sunday closed all entrances to Tahrir Square in preparation for planned demonstrations by the April 6 movement, according to Al-Ahram's Arabic news website.
The youth movement had called for its members to protest on Sunday, 6 April, to commemorate the date of its establishment six years ago.
The closure comes amid fears that the outlawed Muslim Brotherhood would join the protests in an effort to storm the square.
Meanwhile, April 6 founder Ahmed Maher and prominent member Mohamed Adel are currently in detention on charges of illegal protesting, as per a law issued last year banning all demonstrations not pre-approved by authorities.
In March, the April 6 Youth Movement launched a petition calling for the cancellation of the controversial protest law.
The April 6 movement was established in 2008, when it called for a national strike in solidarity with a labour strike in the Nile Delta city of Mahalla and also against then-president Hosni Mubarak.