Iran's Foreign Minister said on Sunday the shooting down of an Israeli jet after it bombed an Iranian site in Syria had shattered Israel's "so-called invincibility", reacting to a critical speech delivered earlier by Israel's premier.

"Israel uses aggression as a policy against its neighbours," Mohammad Javad Zarif told the Munich Security Conference, accusing Israel of "mass reprisals against its neighbours and daily incursions into Syria, Lebanon."

"Once the Syrians have the guts to down one of its planes it's as if a disaster has happened," Zarif said.

He was responding to Benjamin Netanyahu's address to the conference hours before, in which the Israeli prime minister, holding a piece of what he said was an Iranian drone, accused Iran of trying to impose an "empire" across the Middle East.

"What has happened in the past several days is the so-called invincibility (of Israel) has crumbled," Zarif said of Netanyahu's remarks, which followed the Feb. 10 downing of an Israeli F-16 jet.

David Ivry, a former Israeli Air Force chief, told Reuters earlier this month he believed it was the first time an Israeli F-16 was brought down since Israel began using the jets in the 1980s.

Anti-aircraft fire downed the jet as it was returning from a bombing raid on Iran-backed positions in Syria.

It was one of at least eight Israeli planes despatched in response to what Israel said was an Iranian drone's incursion into its airspace earlier on that day.

The jet was hit by a Syrian anti-aircraft missile and crashed in northern Israel, according to an Israeli official.