Kuwaiti authorities arrested several people when hundreds of angry Syrians and local activists stormed the Syrian embassy in the Gulf state on Saturday, the interior ministry said.
"A group of Syrian expats stormed the Syrian embassy in Kuwait, removed the flag and destroyed utilities," the ministry said in a statement.
Security personnel assigned to guard the embassy "fired warning gunshots" but protesters still stormed the embassy which eventually left a number of Kuwaiti security men injured, the ministry said.
Earlier, the independent Kuwait Association for Human Rights said on its Twitter page that at least two protesters were injured in the scramble to flee after embassy guards fired gunshots into the air.
In its statement, the interior ministry said that the Syrian ambassador and other embassy staff escaped unhurt.
Police arrested a number of those who stormed the mission, including several Kuwaitis and authorities were still looking for others, it said.
Kuwaiti activist Abdulaziz al-Mutairi was among those arrested, his friends said in messages posted on Twitter.
Newly elected Islamist MP Osama Munawer called in a statement for the "immediate release of those arrested."
Kuwaiti activists meanwhile called for another protest at the Syrian embassy later in the day.
The demonstration took place after Syrians and activists used Twitter to appeal for the gathering to be held after dawn Muslim prayers, following news about a massacre in Homs.
About 100,000 Syrians work and live in Kuwait.
The demonstration occurred amid reports that Syrian forces killed more than 200 civilians, including women and children, in a "massacre" in the central city of Homs, ahead of a United Nations vote on the repression.