The United Nations Security Council on Monday backed a new push for peace talks in Syria adopted by Russia and the other 14 member states, despite reservations from Venezuela.
It was the first time in two years that the council agreed on a political statement on Syria, which French Deputy Ambassador Alexis Lamek described as "historic."
Venezuela, which has friendly relations with Syria, said it was disassociating itself from parts of the statement calling for a political transition to end the four-year war.
Caracas envoy Rafael Ramirez said the council was setting "a very dangerous precedent" by supporting a transition that he said violated Syria's right to self-determination.
The 16-point statement drafted by France had been under negotiation since UN envoy Staffan de Mistura presented his new approach for peace talks to the council last month.
The peace initiative, set to begin in September, would set up four working groups to address safety and protection, counterterrorism, political and legal issues and reconstruction.
The council demanded that all sides work for an end to the war by "launching a Syrian-led political process leading to a political transition that meets the legitimate aspirations of the Syrian people."
The transition includes "the establishment of an inclusive transitional governing body with full executive powers, which shall be formed on the basis of mutual consent while ensuring continuity of governmental institutions."
The council expressed "grave alarm that the Syria crisis has become the largest humanitarian emergency crisis in the world today," with at least 250,000 dead and 12 million people forced to flee their homes.
The statement was adopted a day after Syrian government air strikes on a rebel-held town near Damascus killed at least 96 people in one of the bloodiest regime attacks in the war.