Egypt's Court of Appeal on Monday ordered the Egyptian Stock Exchange to unfreeze investments held by senior Muslim Brothers Khairat El-Shater and Hassan Malik.
The head of the court sent a letter with the order to the chairman of the stock exchange's clearing house.
Investments held by the wives and minor children of El-Shater and Malik will also be released.
A military court convicted the two men of money laundering in 2007. They were banned from managing their stock investments as part of the sentence.
Both men were released from Tora Prison in March 2011.