Ahly and Egypt defender Ahmed Hegazi will miss the upcoming league fixture at Alexandria's Ittihad due to muscle fatigue.
Hegazi, 26, was forced off in last week's 2-0 league victory over Petrojet after colliding with forward James Teddy in the first half.
"Scans have showed that Hegazi is suffering hamstring muscle fatigue," Ahly football director Sayed Abdel-Hafiz said.
The former Fiorentina center-back was an integral member of Egypt's squad at this year's Africa Cup of Nations, playing all minutes to help his side finish runners-up to champions Cameroon.
He missed Ahly's first few league games through injury before starting eight consecutive matches late last year.
The injury-hit defender, however, was again hampered by another setback to miss four league games in December.
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