US Secretary of State Antony Blinken in a call with Ethiopia's prime minister on Thursday expressed ``grave concern'' about the crisis in the embattled Tigray region and urged ``immediate, full and unhindered humanitarian access to prevent further loss of life,'' a US spokesman said.

There was no immediate comment from Ethiopian officials.

The call is the latest this week that world leaders have held with Prime Minister Abiy Ahmed as Ethiopia faces growing pressure to open Tigray to journalists, independent investigators and far more humanitarian aid.

The Tigray conflict, which has entered its fourth month, remains largely in the shadows. Thousands of people have been killed as Ethiopian and allied forces fight those of the now-fugitive Tigray government that once dominated the country's government for nearly three decades.

Most of the population of 6 million need emergency aid.

Abiy also has spoken this week with the French president and German chancellor, whose governments have expressed similar wishes on opening up Tigray.

Starvation has become a major concern in Tigray. ``Many households are expected to have already depleted their food stocks, or are expected to deplete their food stocks in the next two months,'' according to a new report by the Famine Early Warning Systems Network, which is funded and managed by the US

The report posted Thursday says more parts of central and eastern Tigray likely will enter Emergency Phase 4, a step below famine, in the coming weeks.

Ethiopia's government has denied the presence of soldiers from Eritrea, a bitter enemy of the former Tigray leaders, but witnesses have described widespread looting, killing and other abuses.

``Eritrean forces are almost everywhere in Tigray,'' one man who managed to travel from northern Tigray to the regional capital, Mekele, told The Associated Press this week. He described widespread looting of health centers and people dying from lack of care, with little to no communication or transport links to rural areas. He spoke on condition of anonymity because of concerns for family members.

A senior official in the interim Tigray government, Mesfin Desalegn, in an interview with the pro-governmentUor Eritrean officials for the immediate withdrawal of their forces from Tigray.

The US did not say how Eritrea, one of the world's most secretive nations, responded. Eritrea's information minister in recent days has denounced ``frenzied defamation campaigns.''

The fighting in Tigray has the potential to destabilize other parts of Ethiopia, Africa's second-most populous country and the anchor of the Horn of Africa, as security forces are deployed to the region, the UN humanitarian chief told the Security Council.

Lowcock also said the UN has received reports that food is scarce in markets mainly because it was harvest time when the conflict began. Main supply routes remain cut, cash is scarce and some people are reportedly eating leaves to survive.

Ethiopia's government has said it is reaching more and more people with aid, and it has privately told Biden administration officials that life is returning to ``normalcy.``