Saturday 20 February

AS Kigali (Rwanda) 1-1 CS Sfaxien (Tunisia)
Scorers: Abubakar Lawal 44 / Firas Chaouat 60

Sunday 21 February

US Monastir (Tunisia) 1-0 (5-6) Raja Club Athletic (Morocco) (0-1)
Raja advance to the group stage after winning the penalties after a 1-1 draw on aggregate

Napsa Stars FC (Zambia) 2-2 Gor Mahia (Kenya) (1-0)
Scorers: Austin Banda 18, Emmanuel Mayuka 90+6 / Samuel Onyango 17, Cliffton Ayisi 20
Napsa Stars advance to the group stage with a 3-2 win on aggregate

Namungo FC (Tanzania) 2-6 Primeiro de Agosto (Angola) (0-0)
Primeiro de Agosto advance to the group stage on a 6-2 win on aggregate

Coton Sport (Cameroon) 1-0 AS SONIDEP (Niger) (0-1)
Coton Sport advance to the group stage on penalties after a 1-1 draw on aggregate

DC Motema Pembe (DR Congo) 1-1 Al Ahly Benghazi (Libya) (1-1)
Al Ahly Benghazi advance to the group stage on penalties after a 2-2 draw on aggregate

JS Kabylie (Algeria) 1-0 Stade Malien de Bamako (Mali) (1-2)
Scorer: Souyed 4
JS Kabylie advance to the group stage on the away goal rule after a 2-2 draw on aggregate

Orlando Pirates (South Africa) 1-0 Jwaneng Galaxy FC (Botswana) (3-0)
Scorer: Mntambo 55
Orlando Pirates advance to the group stage on a 4-0 win on aggregate

Cancelled. Etoile Sportive du Sahel (Tunisia) v Young Buffaloes (Eswatini) (2-1)

Rivers United FC (Nigeria) 1-0 Enyimba (Nigeria) (0-1)
Scorer: Omoniwari 43
Enyimba advance to the group stage on penalties after a 1-1 draw on aggregate

Pyramids FC (Egypt) 2-0 Racing Club d Abidjan (Ivory Coast) (2-0)
Scorers: Diego Rolan 4, Ramadan Sobhi 74
Pyramids FC advance to the group stage on a 4-0 aggregate win

ASC Jaraaf de Dakar (Senegal) 1-0 FC Platiniums (Zimbabwe) (1-0)
ASC Jaraaf de Dakar advance to the group stage on a 2-0 aggregate win

Entente Sportive de Setif (Algeria) 0-0 Asante Kotoko – (Ghana) (2-1) 
ES Setif advance to the group stage on a 2-1 aggregate win

Tihad Casablanca (Morocco) 2-1 Nkana FC Kitwe (Zambia) (0-2)
Scorers: Mahmoud Bentayg 4, Ayman Dairani 38/ Simon Mulenga 58
Nkana FC advance to the group stage on a 3-2 aggregate win

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