A trained soldier and football fan, Sheikh Mohamed, took office, as was widely expected, after the death on Friday of his half-brother Sheikh Khalifa bin Zayed Al Nahyan, who had led the country since 2004.
Sheikh Mohamed was unanimously elected by the Federal Supreme Council, made up of rulers of the UAE's seven emirates. He has also been named as ruler of Abu Dhabi, which controls most of the country's oil wealth.
Despite his low profile, and apparent reluctance to speak in public, the 61-year-old’s ambition has been on display in recent years as the UAE built its profile as a regional player.
He was first Gulf leader to strike a deal normalising relations with Israel.
The UAE -- a collection of emirates better known for its skyscrapers, palm-shaped islands and opulent mega attractions -- has in short order built a nuclear power programme and sent a man to space.
And in July 2020 it joined another elite club by sending a probe to Mars, to mark the 50th anniversary of its unification.
Sheikh Mohamed, who was named crown prince of Abu Dhabi in November 2004, is the third son of Sheikh Zayed bin Sultan Al Nahyan -- the founder of the UAE.
He has been serving as deputy commander of the armed forces and chairman of the Executive Council of Abu Dhabi, which controls the emirate's substantial finances.
Born in the capital on March 11, 1961, Sheikh Mohamed was sent to military school in Britain, where he graduated from the famed Royal Military Academy Sandhurst in 1979.
He rapidly rose through the ranks to become air force commander, deputy chief of staff and finally chief of staff in January 1993, and a year later was promoted to the rank of general.
Sheikh Mohamed has forged links in world capitals, particularly in the West.
He is believed to have taken the decision to deploy troops in Yemen in 2015 as part of a Saudi-led military campaign against Iran-backed Houthi rebels.
The Yemen war marked the first protracted military campaign abroad for the UAE and the first time it had to contend with military casualties, with dozens of Emirati soldiers killed.
The UAE, which largely exited the conflict in 2019.
Although Sheikh Mohamed does not often speak in public -- he left the November 2017 inaugural speech of the Louvre Abu Dhabi to Dubai ruler Mohammed bin Rashid -- his reach cannot be underestimated.
Under his leadership, Abu Dhabi has fostered trade and political ties across the region -- including, to a limited extent, with Shiite Iran -- but has sided with the US against Tehran's nuclear programme and with Saudi Arabia on its role in the mainly Sunni Arab world.
At the same time, he crafted for the UAE a reputation of tolerance that contrasts with its conservative neighbours.
In 2017, he announced that Abu Dhabi's Grand Mosque, also known as Sheikh Zayed Mosque after his father, would be renamed the Mariam Umm Issa (Mary, Mother of Jesus) mosque as a means to "consolidate bonds of humanity between followers of different religions".
An avid football fan, Sheikh Mohamed is president of the local club in the oasis of Al-Ain, his father's hometown and the second largest city in Abu Dhabi.
He has also been spotted cycling through the capital in shorts and a helmet.
A keen hunter and a poetry enthusiast, he is married to fellow royal Sheikha Salama bint Hamdan Al Nahyan. The couple has four sons and five daughters.
**This piece was edited by Ahram Online
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