Up to June 30 last year, the Palestinian health ministry reported that Israel killed 37,877 in the war.
However the new peer-reviewed study used data from the ministry, an online survey and social media obituaries to estimate that there were between 55,298 and 78,525 deaths from traumatic injuries in Gaza by that time.
The study's best death toll estimate was 64,260, which would mean the health ministry had under-reported the number of deaths to that point by 41 percent.
That toll represented 2.9 percent of Gaza's pre-war population, "or approximately one in 35 inhabitants," the study said.
The UK-led group of researchers estimated that 59 percent of the deaths were women, children and the elderly.
The toll was only for deaths from traumatic injuries, so did not include deaths from a lack of health care or food, or the thousands of missing believed to be buried under rubble.
On Thursday, Gaza's health ministry said that Israel has kolled 46,006 over 15 months of war.
The UN says the figures are reliable and confirms most of the dead are women and children.
'A good estimate'
The researchers used a statistical method called "capture-recapture" that has previously been used to estimate the death toll in conflicts around the world.
The analysis used data from three different lists, the first provided by the Gaza health ministry of the bodies identified in hospitals or morgues.
The second list was from an online survey launched by the health ministry in which Palestinians reported the deaths of relatives.
The third was sourced from obituaries posted on social media platforms such as X, Instagram, Facebook and WhatsApp, when the identity of the deceased could be verified.
"We only kept in the analysis those who were confirmed dead by their relatives or confirmed dead by the morgues and the hospital," lead study author Zeina Jamaluddine, an epidemiologist at the London School of Hygiene and Tropical Medicine, told AFP.
The researchers scoured the lists, searching for duplicates.
"Then we looked at the overlaps between the three lists, and based on the overlaps, you can come up with a total estimation of the population that was killed," Jamaluddine said.
Patrick Ball, a statistician at the US-based Human Rights Data Analysis Group not involved in the research, has used capture-recapture methods to estimate death tolls for conflicts in Guatemala, Kosovo, Peru and Colombia.
Ball told AFP the well-tested technique has been used for centuries and that the researchers had reached "a good estimate" for Gaza.
Kevin McConway, a professor of applied statistics at Britain's Open University, told AFP that despite uncertainty surrounding estimates from incomplete data, it was "admirable" that the researchers had used three other statistical analysis approaches to check their estimates.
"Overall, I find these estimates reasonably compelling, he added.
'Criticism' expected from both sides
The researchers cautioned that the hospital lists do not always provide the cause of death, so it was possible that people with non-traumatic health problems -- such as a heart attack -- could have been included, potentially leading to an overestimate.
However there were other ways that the war's toll could still be underestimated.
The study did not include missing people. The UN humanitarian agency OCHA has said that around 10,000 missing Palestinians are thought to be buried under the rubble in Gaza.
There are also indirect ways that war can claim lives, such as a lack of healthcare, food, water, sanitation or the spread of disease. All have stricken Gaza since October 2023.
In a non-peer-reviewed letter published in The Lancet in July, another group of researchers used the rate of indirect deaths seen in other conflicts to suggest that the actual Palestinian death toll in Gaza could exceed 186,000 people.
The new study suggested that this projection "might be inappropriate due to obvious differences in the pre-war burden of disease" in Gaza compared to conflicts in countries such as Burundi and East Timor.
Jamaluddine said she expected that "criticism is going to come from different sides" about the new research.
She spoke out against the "obsession" of arguing about death tolls, emphasising that "we already know that there is a lot of high mortality".
*This story was edited by Ahram Online.
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