Real Madrid's Spanish defender #24 Dean Huijsen shoots the ball in front of Villarreal's Senegalese midfielder #18 Pape Gueye during the Spanish league football match between Real Madrid CF and Villarreal CF at the Santiago Bernabeu stadium in Madrid. AFP
He will be replaced by Athletic Bilbao player Aymeric Laporte, the Spanish soccer federation said Wednesday.
The federation said Huijsen reported to the squad on Monday feeling muscle discomfort and medical tests conducted on Wednesday showed he has a muscle injury.
Madrid said Huijsen has been diagnosed with an injury to the soleus muscle in his left leg.
He had played the full Spanish league match against Villarreal on Saturday, which Madrid won 3-1.
Spain coach Luis de la Fuente is already missing several players because of injuries, including midfielder Rodri and forward Lamine Yamal.
Spain hosts Georgia on Saturday and Bulgaria three days later.
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