Napoli's Cameroonian midfielder #99 Andre-Frank Anguissa controls the ball during the UEFA Champions League - league phase day 4 football match between Napoli and Eintracht Frankfurt at the Diego Armando Maradona stadium in Naples. AFP
Anguissa suffered the injury while on international duty with Cameroon.
Napoli said medical tests revealed a “high-grade lesion to his left hamstring.”
The Serie A champions did not specify how long the 29-year-old would be sidelined, but Italian media reported he could be out for three to four months.
Anguissa has been a key figure for Napoli this season, scoring four goals and providing two assists in 15 appearances in all competitions.
Cameroon have been drawn in Group F alongside Ivory Coast, Gabon and Mozambique for the tournament, which kicks off in December.
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