Aryna Sabalenka reacts after losing a ball to Donna Vekic from Croatia during a match of the Dubai Duty Free Tennis Championships in Dubai. AFP
Sabalenka has not played since losing the Australian Open final to Elena Rybakina last month.
"I'm really sorry I have to withdraw from Dubai," said the Belarusian in a statement released by organisers on Friday.
"I have such a special connection with the tournament, the fans and the city. Unfortunately, I am not feeling 100 percent. But I hope to be back next year and wish the tournament a great event."
Swiatek was in action this week in Doha but failed in her bid for a fourth Qatar Open title, losing to Maria Sakkari in the quarter-finals.
"I am sorry to announce that I will not be playing Dubai this year due to a change of schedule," said the six-time Grand Slam champion.
The first round in Dubai gets under way on Sunday.
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