Israeli search and rescue personnel work at the site of a residential building destroyed in an Iranian strike in the northern city of Haifa. AFP
The direct hit on a seven-story building tore through sections of the structure, which has partially collapsed, the military and rescue services said.
The strike took place minutes after the military warned it had detected a new round of missiles fired from Iran at around 1500 GMT.
Elad Edri, chief of staff of Israel's Home Front Command, said that four people were missing.
"We have a major destruction site," he said in a video statement.
Israel's Fire and Rescue Services said later that two of the four people trapped under the rubble had been found dead.
The building was hit by a "direct impact of a missile," a military spokesperson told AFP, confirming it was fired from Iran.
Iran has fired missiles daily at Israel since February 28, in retaliation for joint US-Israeli attacks on the country that have killed several top Iranian leaders, including supreme leader Ali Khamenei and more than 1,900 people in Iran.
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