A group of unknown gunmen fired at a police vehicle in Al-Arish in North Sinai Thursday, leaving three officers seriously injured.
The injured were immediately transferred to Al-Arish general hospital, reported Al-Ahram Arabic news website.
The assailants were riding a motorcycle with no license plate, according to eyewitnesses.
Egypt has witnessed a sharp rise in militant attacks in the Sinai Peninsula since former president Mohamed Morsi was removed by the army on 3 July amid mass protests against his rule.
Over 10 policemen have died in militant attacks since Morsi's ouster.
Hardline Islamist groups based in North Sinai have intensified attacks on police and soldiers over the past two years, exploiting a security and political vacuum following the 2011 uprising that ousted autocratic president Hosni Mubarak.