Both officials discussed the risks posed to the lives of hundreds of civilians and the potential threats to the security and stability of the region resulting from these confrontations, according to a statement by the Egyptian foreign ministry.

Minister Shoukry said Egypt's “deep concern” over the continuation and intensity of military confrontations, particularly the large-scale Israeli airstrikes against the Palestinian people in Gaza.

Egypt’s top diplomat highlighted the Egyptian efforts to de-escalate the situation and achieve the desired ceasefire. He also briefed his counterpart on the Egyptian endeavors to deliver humanitarian aid through the Rafah crossing, despite Israeli airstrikes on Palestinian areas along the crossing point.

Shoukry warned against the expansion of the ongoing conflict, saying this could jeopardize the region's stability and its people's safety.

On his part, the Iranian foreign minister expressed his country's appreciation for Egypt's efforts, especially in supporting the Palestinian cause and providing humanitarian assistance to the Palestinian people.

Earlier today, President Abdel-Fattah El-Sisi said Egypt is intensifying its efforts at all levels to halt the current military confrontations, spare the blood of the Palestinian people, and protect civilians on both the Palestinian and Israeli sides.

According to media reports citing the Palestinian Health Ministry, the Israeli airstrikes have left some 830 Palestinians dead, including 140 children and 105 women, and wounded over 4,250 people.

Israel -- which declared a state of war on Saturday in response to a surprise attack by Hamas in the early hours of the day -- has launched deadly and devastating airstrikes on the population in the Gaza Strip since then, with tens of residential homes and buildings among structures hit -- without prior warning.

Saturday’s Hamas attack, named Operation Al-Aqsa Flood, has resulted in the deaths of approximately 900 Israelis and the capture of tens of others.

The call between the Egyptian and Iranian foreign ministers comes amid recent thawing in relations between the two countries that were ruptured more than four decades ago in the aftermath of the 1979 Islamic Revolution.

Last month, Shoukry met his Iranian counterpart on the sidelines of the United Nations General Assembly meetings to discuss prospects for building trust between Cairo and Tehran.