Twelve supporters of ousted president Mohamed Morsi were arrested on Tuesday after they blocked one of Greater Cairo's main intercity highways, the 26 July Corridor, Al-Ahram's Arabic news website reported.
Over 200 protesters gathered on the road and burned car tyres, delaying traffic in Mohandiseen, one of Giza's busiest neighbourhoods and the start of the highway leading to 6 October City, about 15 km away.
Security forces fired tear gas to disperse the blockade, according to Al-Ahram.
The demonstration was held to denounce Monday's ruling by a Minya court which sentenced 683 pro-Morsi detainees to death in connection to an attack last summer on a police station. The same court also upheld a mass death sentence from last month for 529 people, sentencing 37 to death and the other 492 to life in prison.
The verdicts drew widespread condemnation both inside Egypt and from international rights groups and political figures.
Also on Tuesday, around 250 Morsi supporters gathered in 6 October City to chant slogans against the military and police, according to Al-Ahram. They were later dispersed by security forces, who fired tear gas.
Eight protesters were arrested and three cars were seized that contained Molotov cocktails.
The head of Giza governorate's security directorate, Kamal El-Daly, has ordered the eight detainees to be referred to prosecutors.
Meanwhile, the Muslim Brotherhood-led National Alliance to Support Legitimacy (NASL) called for a new wave of protests to start on Wednesday to denounce Monday's court rulings.