A 60-year-old woman was killed and others, including at least one child, were injured when a three-storey building collapsed in El-Dekheila in western Alexandria.
Civil protection personnel have rescued injured victims from the rubble and are continuing to search for others.
The injured have been transferred to Gamal Hamada Central Hospital.
The incident is the second in a week in Alexandria, after another building collapsed in Al-Attarin district on Friday, causing injuries.
Building collapses are not uncommon in Egypt and are usually attributed to violations of building regulations, illegal building extensions, and lax government oversight.
However, the government has pledged “resolute” measures to end building violations nationwide, especially on agricultural land.
Egypt has seen a significant rise in illegal construction since the security vacuum that followed the 2011 uprising, with many people constructing multi-storey buildings without acquiring the necessary permits or complying with engineering safety standards.