Egypt's Muslim Brotherhood and its allies suffered a strong blow from the state security crackdown, their central coordination has been lost and the bloodshed means anger is now "beyond control," a spokesman said on Thursday.
Gehad El-Haddad also said two of the group's leaders were shot when police raided two protest camps in Cairo of supporters of deposed president Mohamed Morsi on Wednesday, killing hundreds of people.
The bloodshed has made it more difficult for the Brotherhood to persuade its members to stick to peaceful resistance to the government installed by the army after Morsi's overthrow on 3 July, said El-Haddad.
"After the blows and arrests and killings that we are facing emotions are too high to be guided by anyone," he said.
El-Haddad, who spoke to Reuters by Skype and said his movement was restricted because of security checkpoints, could not account for the whereabouts of Brotherhood leaders.
"We can't confirm the whereabouts of all of them yet. Two of the top leaders have been shot but are not dead as far as I know. About six of them have lost their sons and daughters," he said. "It's a bad blow, a very strong blow."
He added: "It's not about Morsi anymore. Are we going to accept a new military tyranny in Egypt or not?"
He said the death toll was eight or nine times bigger than the official toll of about 500.