Members of the Syrian Arab Red Crescent unload aid parcels from a lorry on February 13, 2016 in the rebel-held city of Douma, northeast of the capital Damascus. (AFP)
A convoy carrying medical aid entered the besieged rebel-controlled Douma area near the Syrian capital on Saturday, the official SANA news agency reported, citing the Syrian Red Crescent.
The aid consists of medicines and also milk for children, said Syrian Red Crescent director of operations Hazem Bakla.
The United Nations Office for the Coordination of Humanitarian Affairs (OCHA) confirmed the aid delivery to Douma in the Eastern Ghouta, a rebel stronghold east of Damascus besieged since 2013.
According to UN figures, some 486,700 people in Syria currently live in areas besieged by either government or rebel forces.
Scores are reported to have died of malnutrition or because of a lack of medical treatment.
On Friday, the world body said it hoped to deliver aid to people in besieged Syrian cities "without delay", after world powers agreed a plan to cease hostilities in the war-wracked country.
The United Nations has said that only around a dozen of 116 access requests to reach people in need have been granted by the Syrian authorities.
The United States and Russia agreed Friday in Munich on a "cessation of hostilities" in Syria within a week with the aim of relaunching the peace process and halting the exodus of civilians.
The two countries and their main allies within the International Syria Support Group also agreed on "immediate" access to humanitarian aid for needy civilians.