Michelle Bachelet, UN High Commissioner for Human Rights, speaks to the media about the Tigray region of Ethiopia during a press conference at the European headquarters of the United Nations in Geneva, Switzerland, Nov. 3, 2021. AP
Shireen Abu Akleh, 51, was shot dead as she covered an Israeli army raid.
UN human rights chief Michelle Bachelet's office said it was on the ground and trying to verify the facts.
"We are appalled at the killing of journalist Shireen Abu Akleh while covering an Israeli military operation in Jenin, Palestine," UN human rights chief Michelle Bachelet's office said on Twitter.
"Our office is on the ground verifying the facts.
"We urge an independent, transparent investigation into her killing. Impunity must end."
The Qatar-based TV channel Al Jazeera charged that Israeli forces deliberately and "in cold blood" shot Abu Akleh in the head during the unrest in the Jenin refugee camp earlier on Wednesday.
While Israel's Prime Minister Naftali Bennett said it was "likely" that "armed Palestinians, who were indiscriminately firing at the time, were responsible for the unfortunate death of the journalist".