Raisi acknowledged that the Islamic Republic had "weaknesses and shortcomings,'' but repeated the official line that the unrest sparked last month by the death of a woman in the custody of the country's morality police was nothing short of a plot by Iran's enemies.
"Today the country's determination is aimed at cooperation to reduce people's problems,'' he told a parliament session. "Unity and national integrity are necessities that render our enemy hopeless.''
His claims echoed those of Iran's supreme leader Ayatollah Ali Khamenei, who blamed the United States and Israel, the country's adversaries, for inciting the unrest in his first remarks on the nationwide protests on Monday.
It's a familiar tactic for Iran's leaders, who have been mistrustful of Western influence since the 1979 Islamic Revolution.
Iran has also blamed the unrest on Kurdish opposition groups in the country's northwest that operate along the border with neighboring Iraq.
On Tuesday, Iran's paramilitary Revolutionary Guard bombed three bases belonging to Kurdish militant groups in Iraq's semi-autonomous Kurdish region with drones and artillery, the semiofficial Tasnim news agency reported, without elaborating on casualties.
It was the latest in a wave of Iranian bombardments that killed at least nine people last month.
The protests, which emerged in response to the death of 22-year-old Mahsa Amini after her arrest for allegedly violating the Islamic Republic's strict dress code, have embroiled dozens of cities across the country and evolved into the most widespread challenge to Iran's leadership in years.
A series of festering crises have helped fuel public rage, including the country's political repression, ailing economy and global isolation.
The scope of the ongoing unrest, the most sustained in over a decade, remains unclear as witnesses report spontaneous gatherings across the country featuring small acts of defiance, protesters shouting slogans from rooftops, cutting their hair and burning their state-mandated headscarves.
The hardline Kayhan daily on Tuesday tried to downplay the scale of the movement, saying that "anti-revolutionaries,"or those opposed to the Islamic Republic, "are in the absolute minority, possibly 1%.''
But another hardline newspaper, the Jomhuri Eslami daily, cast doubt on government claims that foreign countries were to blame for the country's turmoil.
"Neither foreign enemies nor domestic opposition can take cities into a state of riot without a background of discontent,'' its editorial read.
Iran's security forces have sought to disperse demonstrations with tear gas, metal pellets, and in some cases live fire, rights groups say.
Iran's state TV reports that violent confrontations between protesters and the police have killed at least 41 people, but human rights groups say the number is much higher.
An escalating crackdown on the press, with dozens of journalists arrested in the last few weeks, has stifled most independent reporting on sensitive issues such as the deaths of protesters.
The recent disappearance and death of a 17-year-old girl in Tehran, however, has unleashed an outpouring of anger on Iranian social media.
Nika Shahkarami, who lived in the capital with her mother, vanished one night last month during the protests in Tehran, her uncle Kianoush Shakarami told Tasnim news agency.
She was missing for a week before her lifeless body was found in a Tehran street and was returned to her family, Tasnim reported, adding relatives had not received official word on how she died.
Foreign-based Iranian activists allege she died in police custody, with hundreds circulating her photo and using her name as hashtag online for the protest movement.
The prosecutor in the western Lorestan province, Dariush Shahoonvand, denied any wrongdoing by authorities and said was buried in her village Monday.
"Foreign enemies have tried to create a tense atmosphere after this incident,'' he told the Hamshari daily, without elaborating on what happened.
As the new academic year began this week, demonstrations spread to university campuses, long considered sanctuaries in times of turmoil.
Videos on social media showed students expressing solidarity with peers who had been arrested and calling for the end of the Islamic Republic. Roiled by the unrest, many universities moved classes online this week.
The prestigious Sharif University of Technology in Tehran became a battlefield on Sunday as security forces surrounded the campus from all sides and fired tear gas at protesters who were holed up inside a parking lot, preventing them from leaving.
In one video on Monday, students at Tarbiat Modares University in Tehran marched and chanted, ``Jailed students must be freed" In another, students streamed through Khayyam University in the conservative city of Mashhad, shouting, "Sharif University has become a jail! Evin Prison has become a university!'' referring to Iran's notorious prison in Tehran.
Protests also appeared to grip gender-segregated high schools across Iran, where groups of young schoolgirls waved their hijabs and chanted "Woman! Life! Freedom!'' in the city of Karaj west of the capital and in the Kurdish city of Sanandaj on Monday, according to widely shared footage.
The response by Iran's security forces has drawn widespread condemnation. On Monday, President Joe Biden said his administration was "gravely concerned about reports of the intensifying violent crackdown."
The British foreign office summoned the Iranian ambassador in London.
"The violence leveled at protests in Iran by the security forces is truly shocking,'' said British Foreign Secretary James Cleverly.
Security forces have rounded up an untold number of demonstrators, as well as artists who have voiced support for the protests. Local officials report at least 1,500 arrests.
Shervin Hajipour, a singer who emerged as a protest icon for his wildly popular song inspired by Amini's death, was detained last week. His lawyer said he was released on bail Tuesday and rejoined his family in the northern city of Babolsar.
In his somber ballad, "For the sake of,'' he sings of why Iranians are rising up in protest.
"For dancing in the streets," he intones. "For my sister, for your sister, for our sisters.''