The protest followed clashes between police and protesters at the same location on Friday that the ministry said left 21 police officers injured and three police stations damaged, an AFP reporter said.
Large numbers of police moved quickly to disperse Saturday's protest and men in civilian clothes and masks, armed with clubs, were seen moving through the streets searching for protesters.
Tens of thousands of protesters took to the streets on Friday demanding the resignation of the country's interim prime minister, an ally of ousted leader Zine El Abidine Ben Ali.
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