File Photo: Former US secretary of state Madeleine Albright speaks during the Center for American Progress (CAP) 10th Anniversary Conference in Washington, DC, October 24, 2013.AFP
Tapped by then-president Bill Clinton first as ambassador to the United Nations, then as US top diplomat, Albright was one of the most influential stateswomen of her generation.
In mourning her passing, Clinton said Albright had been "a force for freedom, democracy, and human rights," calling her death an "immense loss to the world."
In announcing his choice of Albright to head the State Department, Clinton said gender "had nothing to do with her getting the job" and that she was the most qualified candidate.
Albright, however, was aware of the significance of the appointment.
"It used to be that the only way a woman could truly make her foreign policy views felt was by marrying a diplomat and then pouring tea on an offending ambassador's lap," she once said in a speech to the Women in Foreign Policy Group.
"Today, women are engaged in every facet of global affairs."
Following news of her death, State Department spokesman Ned Price said she had been a "trailblazer as the first female secretary of state and quite literally opened doors for a large element of our workforce."
Albright took the helm of the State Department in the post-Cold War world in which the United States had emerged as the single superpower, leading crucial discussions with world leaders on arms control, trade, terrorism, and the future of NATO.
Not since Margaret Thatcher governed Britain had a woman held such a position of global influence.
Described by her family as a "tireless champion of democracy and human rights," Albright was awarded the nation's highest civilian honor, the Presidential Medal of Freedom, by President Barack Obama in 2012.
Born Marie Jana Korbelova in Czechoslovakia on May 15, 1937, Albright came to the United States as a refugee with her family in 1948 and became a US citizen in 1957.
Her father, Josef Korbel, a diplomat, had converted from Judaism to Catholicism after the family fled to London in 1939 to escape the Nazis.
Albright said she only learned about her Jewish origins late in life and the fact that three of her grandparents had perished in concentration camps.
'Short, Noisy Type'
Fluent in English, Czech, French, and Russian, Albright earned her undergraduate degree from Wellesley College.
Albright earned her doctorate in political science at Columbia University and went to work for Democratic senator Edmund Muskie.
She later joined the National Security Council in the White House of president Jimmy Carter, serving under his national security advisor Zbigniew Brzezinski, her former professor at Columbia.
After Carter's defeat, Albright began teaching at Georgetown University in Washington but remained an influential voice in Democratic foreign policy-making circles.
She was named US ambassador to the United Nations by Clinton in 1993 and served in that role until 1997 when she became secretary of state.
One of her final voyages in the post was an official visit to North Korea, where she met with then-leader Kim Jong-Il.
In an interview with AFP as she prepared to leave the State Department in 2001, Albright said she would remain involved in foreign policy.
"I am not going to be a wallflower," Albright said.
"I also have never thought of myself as the tall, silent type, so I will be the short, noisy type and I am going to stay out there," she said. "I love foreign policy, I am passionately interested in how the world evolves."
Just a month ago, The New York Times published an opinion piece by Albright in which she argued that Russian leader Vladimir Putin would be making a "historic error" if he invaded Ukraine.
Albright married Joseph Albright in 1959. They had three daughters and divorced in 1982.
Her memoirs, "Madam Secretary," were published in 2003.