Rejecting all violence against all civilians, Zein passionately told Morgan that Muslims and Christians lived side by side and in peace with their Jewish neighbours in the Arab countries before the creation of the state of Israel and the dispossession of the Palestinian people.
"The United States has given permission for Israel to [commit] genocide on the ground," she said.
"I have accused Israel of genocide. I am accusing Israel of genocide. It is genocide," Zein insisted.
"Israel has the right to defend itself," exclaimed Morgan.
But Zein fired back at Morgan: "Against what? Against women and children? How many Palestinians died?"
"The sick relationship between the US and Israel is putting the whole world in Jeopardy," Zein stressed.
The Western world was raising Israel as "a spoiled brat" that has violated international law time and again, she added.
"You and the Western media are unable to say no to a country that has grown up to be "a sociopath," Zein, the editor-in-chief of Scoop Empire, told Morgan.
I have people in New York who called me and said they were fired from their jobs because they declared support for the Palestinians, she said.
Anchors and producers in the West are emailing their networks asking why they are not showing the other side.
"Why aren't you showing the other side?" she challenged Morgan.
Not a "war between two sides"!
The current conflict in Gaza "is not a war," she insisted, in responding to his attempts to talk about "a war between two sides."
"A war assumes that both sides are on equal footing," she lambasted Morgan for attempting to equate "violence on both sides," she said.
Israel ignores UN resolutions, has the backing of the United States, the backing of the European Union, and the backing of Britain that started this whole farce," Zein reminded Morgan.
As Morgan tried to portray Zein's impassioned defense of the Palestinians under Israeli bombardment as too abstract and lacking in the substance needed for a concrete proposal for a resolution of the conflict, Zein said: Empower the United Nations to enforce international law so that Israel can stop making mockery of the United Nations.
"I am giving you a solution," which is to end the occupation, she insisted.
"If Palestinian women under occupation give births sometimes at Israeli checkpoints, Palestinians are being jailed in Israeli prisons, and if you are mercilessly bombarding Palestinians - then you are breeding a Hamas."
"I hear you and I appreciate your opinion," Morgan said.
Call for a ceasefire then!" Zein told Morgan.
"That's not my job. My job is to interview people on the issue," Morgan responded.
"Your job seems to be conducting sensational interviews," Zein said as she took off her mic.
After confronting a CNN big shot!
Earlier this week, Zein made international headlines after confronting CNN's Clarissa Ward on the Rafah border crossing - in the presence of activists and international reporters - as Israel continued to deny basic humanitarian aid to 2.3 million Palestinians under its airstrikes, on her network's bias and anti-Palestinian fake news.
In a video that went viral, Zein is seen challenging Ward, the chief international correspondent for CNN, about her complicity in the airing of a fake news segment that depicted "senseless Palestinian bombings against Israelis."
Days earlier, live footage showed Ward agreeing on air to go along with her network producer's instructions to pretend to duck "under duress" during a "senseless bombing by Hamas," as the American network continued unabashed support for Israeli airstrikes on Palestinians in the Gaza Strip.
Tonight, as she decried Piers Morgan's refusal to denounce Israeli occupation or its war crimes against the Palestinians, Zein made a passionate case on his show against the Israeli occupation and Israel's long history of oppressing the Palestinian people.
She called for an immediate ceasefire, the establishment of a Palestinian state, and holding Israel accountable by the UN under international law.
After Bassem Youssef
On Wednesday, Zein became the second Egyptian public figure to expose Morgan's biases on his YouTube channel - 1.89 million subscribers - in less than one week.
Last week, in a similar interview with Piers Morgan, World-renowned Egyptian satirist Bassem Youssef took the British broadcaster to task, exposing - with superb wit - his attempts to portray the current conflict as a result of the Hamas attack on 7 October and not a decades-old policy of dispossession of the Palestinian people by Israel
Bassem Youssef's interview with Morgan garnered millions of views on social media platforms in the Arab world and in Western countries.