Jaziri, who has been in good form recently, gained a penalty in the 16th minute which was converted by Ahmed 'Zizo' Sayed to open the scoring.
Zizo doubled the lead with a curling shot from outside the area before Jaziri scored the third goal with a deflected shot.
After the break, Jaziri capitalized on a mistake by the Arab Contractors keeper to score his second and Zamalek's fourth goal, followed by a wonder strike from the skipper Mahmoud 'Shikabala' Abdel-Razek from an impossible angle.
Jaziri completed his hat-trick with a close-range header, while Fadi Farid scored a consolation goal for Arab Contractors.
The win was a morale boost for Zamalek, who have struggled in the league this season, and will face Pyramids FC in the Egypt Cup semi-finals.
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