Congolese midfielder Joseph Bakasu scored the winner two minutes after halftime, easing Wydad’s task ahead of the second leg next week.
In contrast, Tunisian side Etoile Sportive du Sahel suffered a 2-0 defeat away to Kenya’s Nairobi United in Nairobi on Sunday.
The two-time Confederation Cup winners face a tough challenge at home next week as they attempt to overturn the deficit in Sousse.
Elsewhere, Congolese club Otoho d’Oyo claimed a 1-0 away win over Mozambique’s Ferroviário Maputo, while Burundi’s Flambeau du Centre played out a 1-1 draw with Tanzania’s Singida Black Stars.
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