Real Madrid's Brazilian forward #11 Rodrygo reacts during the UEFA Champions League, league phase day 3 football match between Real Madrid CF and Borussia Dortmund at the Santiago Bernabeu stadium in Madrid on October 22, 2024. Photo: AFP
"Following the tests carried out today... he has been diagnosed with a muscle injury in the right femoral biceps," the club said in a statement on Thursday.
He is expected to be sidelined for around three weeks, Spanish media reported.
Rodrygo played a key role in Real's comeback win against the Germans on Tuesday, keeping the ball in play to set up Lucas Vazquez for the goal that put the European champions back in the lead after they had trailed 2-0. They went on to win 5-2.
After his involvement in the goal, the 23-year-old was substituted.
Goalkeeper Thibaut Courtois will also sit out the Clasico after suffering an adductor injury in the Dortmund game.
The Belgian is expected to be replaced by the Ukrainian Andriy Lunin for the Barcelona game at the Bernabeu.
Barca warmed up for Spain's biggest fixture with an impressive 4-1 home win against Bayern Munich on Wednesday, with Raphinha grabbing a hat-trick.
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