Real Madrid striker Karim Benzema
"Benzema has no chance of playing, he did not even train with us today," he told a news conference following a training session.
Benzema was substituted in the 75th minute of France's goalless friendly draw with Croatia on March 29 after suffering an injury to his thigh.
The 23-year-old missed Real's 1-0 league loss at home to Sporting Gijon on Saturday. He has scored eight goals in his last five games for the club.
Mourinho said a decision as to whether or not Real Portuguese striker Cristiano Ronaldo and Brazilian winger Marcelo Vieira will be available to play Tottenham will be made later on Monday.
Ronaldo suffered a recurrence of a thigh injury last week, while Marcelo is also fighting his way back from injury.
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