Bolt was a huge draw at the Olympic Stadium last year where almost 50,000 people turned up to watch the world's fastest man.
He didn't disappoint either by overhauling Powell with a late surge to win the 100m in 9.91sec.
Five-time world champion Bolt will open his pre-Olympic season in Europe competing in the Golden Spike event in the eastern Czech city of Ostrava on May 25.
After Rome he will compete in the Oslo leg of the Diamond League meet on June 7, as he prepares for the Olympic Games in London this summer.
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