Third seed Simona Halep has withdrawn from the Miami Open singles and doubles events due to a right shoulder injury, the Romanian said on Saturday.
Halep, who received a bye into the second round where she beat France's Caroline Garcia in three sets, was set to play Latvian Anastasija Sevastova, who will now receive a walkover and advance to the last-16.
Halep, the reigning Wimbledon champion, said she began to feel pain after practice sessions at her first tournament since a quarter-final exit at the Australian Open last month.
"I'm very sorry I have to pull out of singles and doubles at the Miami Open, but my injury doesn't let me play here as I expected," Halep, who had partnered with Angelique Kerber in the doubles, said.
"I'm sad that I can't continue, I wanted to come here to give my best and play many matches but unfortunately I can't. Hopefully next year I will be back healthy and better."
Halep's withdrawal is a blow for the March 22-April 4 tournament, which has already seen Serena Williams pull out to recover from oral surgery, while Roger Federer, Rafa Nadal, Novak Djokovic and Dominic Thiem have all skipped the ATP 1000 event.
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