Studies show how skin cancer evades promising drug

Reuters, Friday 26 Nov 2010

U.S. researchers have uncovered several ways in which melanoma can outsmart a promising experimental cancer pill called PLX4032, a finding that could lead to new drugs to keep the deadly skin cancer at bay,

U.S. researchers have uncovered several ways in which melanoma can outsmart a promising experimental cancer pill called PLX4032, a finding that could lead to new drugs to keep the deadly skin cancer at bay, the teams said on Wednesday. Researchers at the University of California, Los Angeles discovered two different resistance mechanisms that explain how melanoma stops responding to treatment with PLX4032, and a separate team at the Broad Institute of Massachusetts Institute of Technology and Harvard in Cambridge, Massachusetts, discovered a third.

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